Bedside to Bench to Bedside Research: Estrogen Receptor Beta Ligand as a Candidate Neuroprotective Treatment for Multiple Sclerosis

Protective effects of pregnancy during MS have led to clinical trials of estriol, the pregnancy estrogen, in MS. Since estriol binds to estrogen receptor (ER) beta, ER beta ligand could represent a “next generation estriol” treatment. Here, ER beta ligand treatment was protective in EAE in both sexe...

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Pubblicato in:J Neuroimmunol
Autori principali: Itoh, Noriko, Kim, Roy, Peng, Mavis, DiFilippo, Emma, Johnsonbaugh, Hadley, MacKenzie-Graham, Allan, Voskuhl, Rhonda R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806698/
https://ncbi.nlm.nih.gov/pubmed/27771018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.09.017
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