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Bedside to Bench to Bedside Research: Estrogen Receptor Beta Ligand as a Candidate Neuroprotective Treatment for Multiple Sclerosis

Protective effects of pregnancy during MS have led to clinical trials of estriol, the pregnancy estrogen, in MS. Since estriol binds to estrogen receptor (ER) beta, ER beta ligand could represent a “next generation estriol” treatment. Here, ER beta ligand treatment was protective in EAE in both sexe...

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Dades bibliogràfiques
Publicat a:J Neuroimmunol
Autors principals: Itoh, Noriko, Kim, Roy, Peng, Mavis, DiFilippo, Emma, Johnsonbaugh, Hadley, MacKenzie-Graham, Allan, Voskuhl, Rhonda R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806698/
https://ncbi.nlm.nih.gov/pubmed/27771018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.09.017
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