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ATP is stored in lamellar bodies to activate vesicular P2X(4) in an autocrine fashion upon exocytosis
Vesicular P2X(4) receptors are known to facilitate secretion and activation of pulmonary surfactant in the alveoli of the lungs. P2X(4) receptors are expressed in the membrane of lamellar bodies (LBs), large secretory lysosomes that store lung surfactant in alveolar type II epithelial cells, and bec...
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| Publicado no: | J Gen Physiol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5806682/ https://ncbi.nlm.nih.gov/pubmed/29282210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711870 |
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