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Surfactant Secretion in LRRK2 Knock-Out Rats: Changes in Lamellar Body Morphology and Rate of Exocytosis

Leucine-rich repeat kinase 2 (LRRK2) is known to play a role in the pathogenesis of various diseases including Parkinson disease, morbus Crohn, leprosy and cancer. LRRK2 is suggested to be involved in a number of cell biological processes such as vesicular trafficking, transcription, autophagy and l...

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Detalhes bibliográficos
Main Authors: Miklavc, Pika, Ehinger, Konstantin, Thompson, Kristin E., Hobi, Nina, Shimshek, Derya R., Frick, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897396/
https://ncbi.nlm.nih.gov/pubmed/24465451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084926
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