Antibodies to PcpA and PhtD protect mice against Streptococcus pneumoniae by a macrophage- and complement-dependent mechanism

Currently marketed Streptococcus pneumoniae (Spn) vaccines, which contain polysaccharide capsular antigens from the most common Spn serotypes, have substantially reduced pneumococcal disease rates but have limited coverage. A trivalent pneumococcal protein vaccine containing pneumococcal choline-bin...

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Detalles Bibliográficos
Publicado en:Hum Vaccin Immunother
Main Authors: Visan, Lucian, Rouleau, Nicolas, Proust, Emilie, Peyrot, Loïc, Donadieu, Arnaud, Ochs, Martina
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806646/
https://ncbi.nlm.nih.gov/pubmed/29135332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1403698
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