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CD4(+) T-Cell Reactivity to Orexin/Hypocretin in Patients With Narcolepsy Type 1
INTRODUCTION: Narcolepsy type 1 is accompanied by a selective loss of orexin/hypocretin (hcrt) neurons in the lateral hypothalamus caused by yet unknown mechanisms. Epidemiologic and genetic associations strongly suggest an immune-mediated pathogenesis of the disease. METHODS: We compared specific T...
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| Publicado no: | Sleep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5806576/ https://ncbi.nlm.nih.gov/pubmed/28364420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsw070 |
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