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Localized Loss of Hypocretin (Orexin) Cells in Narcolepsy Without Cataplexy

STUDY OBJECTIVES: Narcolepsy with cataplexy is characterized by a loss of approximately 90% of hypocretin (Hcrt) neurons. However, more than a quarter of narcoleptics do not have cataplexy and have normal levels of hypocretin in their cerebrospinal fluid, raising the possibility that their disease i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thannickal, Thomas C., Nienhuis, Robert, Siegel, Jerome M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associated Professional Sleep Societies, LLC 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717206/
https://ncbi.nlm.nih.gov/pubmed/19725250
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