Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies

The β-hemoglobinopathies sickle cell anemia and β-thalassemia are the focus of many gene-therapy studies. A key disease parameter is the abundance of globin chains because it indicates the level of anemia, likely toxicity of excess or aberrant globins, and therapeutic potential of induced or exogeno...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Methods
Main Authors: Loucari, Constantinos C., Patsali, Petros, van Dijk, Thamar B., Stephanou, Coralea, Papasavva, Panayiota, Zanti, Maria, Kurita, Ryo, Nakamura, Yukio, Christou, Soteroulla, Sitarou, Maria, Philipsen, Sjaak, Lederer, Carsten W., Kleanthous, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806072/
https://ncbi.nlm.nih.gov/pubmed/29325430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2017.190
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