Mechanism informed repurposing of minocycline overcomes resistance to topoisomerase inhibition for peritoneal carcinomatosis

Mechanism-inspired drug repurposing that augments standard treatments offers a cost-effective and a rapid route toward addressing the burgeoning problem of plateauing of effective therapeutics for drug-resistant micrometastases. We show that the antibiotic minocycline, by its ability to minimize DNA...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cancer Ther
Main Authors: Huang, Huang-Chiao, Liu, Joyce, Baglo, Yang, Rizvi, Imran, Anbil, Sriram, Pigula, Michael, Hasan, Tayyaba
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805648/
https://ncbi.nlm.nih.gov/pubmed/29167313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0568
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker