Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer

The complex interplay between cancer cells and their microenvironment remains a major challenge in the design and optimization of treatment strategies for pancreatic ductal adenocarcinoma (PDAC). Recent investigations have demonstrated that mechanistically distinct combination therapies hold promise...

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Опубликовано в: :Biomaterials
Главные авторы: Broekgaarden, Mans, Anbil, Sriram, Bulin, Anne-Laure, Obaid, Girgis, Mai, Zhiming, Baglo, Yan, Rizvi, Imran, Hasan, Tayyaba
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934357/
https://ncbi.nlm.nih.gov/pubmed/31494503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.119421
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