Deep sustained response to daratumumab monotherapy associated with T-cell expansion in triple refractory myeloma

BACKGROUND: Daratumumab, a human CD38 monoclonal antibody that has direct on-tumor and immunomodulatory mechanisms of action, demonstrated clinical benefit as monotherapy or in combination with established regimens in patients with multiple myeloma with one or more prior lines of therapy. CASE PRESE...

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Bibliografische gegevens
Gepubliceerd in:Exp Hematol Oncol
Hoofdauteurs: Usmani, Saad Z., Khan, Imran, Chiu, Christopher, Foureau, David, Druhan, Lawrence J., Rigby, Katherine, Casneuf, Tineke, Sasser, A. Kate
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Case Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804097/
https://ncbi.nlm.nih.gov/pubmed/29445583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-018-0096-7
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