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Deep sustained response to daratumumab monotherapy associated with T-cell expansion in triple refractory myeloma

BACKGROUND: Daratumumab, a human CD38 monoclonal antibody that has direct on-tumor and immunomodulatory mechanisms of action, demonstrated clinical benefit as monotherapy or in combination with established regimens in patients with multiple myeloma with one or more prior lines of therapy. CASE PRESE...

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Библиографические подробности
Опубликовано в: :Exp Hematol Oncol
Главные авторы: Usmani, Saad Z., Khan, Imran, Chiu, Christopher, Foureau, David, Druhan, Lawrence J., Rigby, Katherine, Casneuf, Tineke, Sasser, A. Kate
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804097/
https://ncbi.nlm.nih.gov/pubmed/29445583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-018-0096-7
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