NLRP2 is a suppressor of NF-ƙB signaling and HLA-C expression in human trophoblasts(†,‡)

During pregnancy, fetal extravillous trophoblasts (EVT) play a key role in the regulation of maternal T cell and NK cell responses. EVT display a unique combination of human leukocyte antigens (HLA); EVT do not express HLA-A and HLA-B, but do express HLA-C, HLA-E, and HLA-G. The mechanisms establish...

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Bibliographic Details
Published in:Biol Reprod
Main Authors: Tilburgs, Tamara, Meissner, Torsten B., Ferreira, Leonardo M. R., Mulder, Arend, Musunuru, Kiran, Ye, Junqiang, Strominger, Jack L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803763/
https://ncbi.nlm.nih.gov/pubmed/28340094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/iox009
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