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An intramolecular interaction of UHRF1 reveals dual control for its histone association

UHRF1 (Ubiquitin-like, containing PHD and RING Finger domains, 1) is one of the essential components of mammalian DNA methylation machinery. Chromatin association of UHRF1 is controlled via an interplay between its intramolecular interaction and dual recognition of histone H3 trimethylated at lysine...

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Détails bibliographiques
Publié dans:Structure
Auteurs principaux: Gao, Linfeng, Tan, Xiao-Feng, Zhang, Shen, Wu, Tianchen, Zhang, Zhi-Min, Ai, Hui-wang, Song, Jikui
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5803408/
https://ncbi.nlm.nih.gov/pubmed/29395786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.12.016
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