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An intramolecular interaction of UHRF1 reveals dual control for its histone association
UHRF1 (Ubiquitin-like, containing PHD and RING Finger domains, 1) is one of the essential components of mammalian DNA methylation machinery. Chromatin association of UHRF1 is controlled via an interplay between its intramolecular interaction and dual recognition of histone H3 trimethylated at lysine...
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| Udgivet i: | Structure |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803408/ https://ncbi.nlm.nih.gov/pubmed/29395786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.12.016 |
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