Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia

Mood instability is a core clinical feature of affective and psychotic disorders. In keeping with the Research Domain Criteria approach, it may be a useful construct for identifying biology that cuts across psychiatric categories. We aimed to investigate the biological validity of a simple measure o...

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Bibliographic Details
Published in:Transl Psychiatry
Main Authors: Ward, Joey, Strawbridge, Rona J., Bailey, Mark E. S., Graham, Nicholas, Ferguson, Amy, Lyall, Donald M., Cullen, Breda, Pidgeon, Laura M., Cavanagh, Jonathan, Mackay, Daniel F., Pell, Jill P., O’Donovan, Michael, Escott-Price, Valentina, Smith, Daniel J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802589/
https://ncbi.nlm.nih.gov/pubmed/29187730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0012-7
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