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Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons

Tau is a neuronal microtubule-associated protein with countless physiological functions. Although the detrimental effects of insoluble aggregated Tau have been widely studied, recent evidence supports the notion that soluble Tau (composed mostly of monomers and dimers) is also toxic for neurons. Her...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Bolós, M, Pallas-Bazarra, N, Terreros-Roncal, J, Perea, JR, Jurado-Arjona, J, Ávila, J, Llorens-Martín, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802513/
https://ncbi.nlm.nih.gov/pubmed/29217824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-017-0013-6
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