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mTOR signaling in skeletal development and disease

The mammalian/mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that integrates inputs from nutrients and growth factors to control many fundamental cellular processes through two distinct protein complexes mTORC1 and mTORC2. Recent mouse genetic studies have established th...

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Bibliografiske detaljer
Udgivet i:Bone Res
Main Authors: Chen, Jianquan, Long, Fanxin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802487/
https://ncbi.nlm.nih.gov/pubmed/29423330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-017-0004-5
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