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Identification of a novel compound heterozygous mutation of the CYP21A2 gene causing 21-hydroxylase deficiency in a Chinese pedigree

21-Hydroxylase deficiency (21-OHD) is the most common cause of congenital adrenal hyperplasia. Inherited in an autosomal recessive manner, 21-OHD is caused by mutations in the cytochrome P450 family 21 subfamily A member 2 (CYP21A2) gene. The present study was designed to investigate the genetic cha...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Liu, Jia, Zhang, Xiujuan, Zhang, Haiqing, Fang, Li, Xu, Jin, Guan, Qingbo, Xu, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802198/
https://ncbi.nlm.nih.gov/pubmed/29328376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8391
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