Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer

BACKGROUND: Genome-wide studies identified pan-cancer genes and shared biological networks affected by epigenetic dysregulation among diverse tumor entities. Here, we systematically screened for hypermethylation of DNA damage repair (DDR) genes in a comprehensive candidate-approach and exemplarily i...

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Библиографические подробности
Опубликовано в: :Clin Epigenetics
Главные авторы: Mijnes, Jolein, Veeck, Jürgen, Gaisa, Nadine T., Burghardt, Eduard, de Ruijter, Tim C., Gostek, Sonja, Dahl, Edgar, Pfister, David, Schmid, Sebastian C., Knüchel, Ruth, Rose, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802064/
https://ncbi.nlm.nih.gov/pubmed/29445424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0447-6
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