Global Level of Plasma DNA Methylation is Associated with Overall Survival in Patients with Hepatocellular Carcinoma

BACKGROUND: The impact of folate deficiency on global DNA methylation is uncertain. It also is unclear whether global DNA methylation is associated with outcome in HCC. LINE-1 methylation levels, as a surrogate marker of global methylation, may be influenced by folate deficiency. However, the intera...

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Detalhes bibliográficos
Publicado no:Ann Surg Oncol
Main Authors: Yeh, Chih-Ching, Goyal, Abhishek, Shen, Jing, Wu, Hui-chen, Strauss, Joshua A., Wang, Qiao, Gurvich, Irina, Safyan, Rachael A., Manji, Gulam A., Gamble, Mary V., Siegel, Abby B., Santella, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801698/
https://ncbi.nlm.nih.gov/pubmed/28593503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-017-5913-4
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