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Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis

Staphylococcus aureus is responsible for a significant amount of devastating disease. Its ability to colonize the host and cause infection is supported by a variety of proteins that are dependent on the cofactor heme. Heme is a porphyrin used broadly across kingdoms and is synthesized de novo from c...

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Bibliographic Details
Published in:mBio
Main Authors: Choby, Jacob E., Grunenwald, Caroline M., Celis, Arianna I., Gerdes, Svetlana Y., DuBois, Jennifer L., Skaar, Eric P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801465/
https://ncbi.nlm.nih.gov/pubmed/29437922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02287-17
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