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NDUFA4 enhances neuron growth by triggering growth factors and inhibiting neuron apoptosis through Bcl-2 and cytochrome C mediated signaling pathway

Dandy-Walker malformation (DWM) is the most prevalent congenital malformation in cerebellum, however, pathological mechanism of DWM has not been fully clarified. This study aims to investigate effects of NDUFA4 on growth of neurons. LV5-NDUFA4 and LV3-NDUFA4-RNAi lentivirus were constructed and tran...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Fu, Fang, Li, Yan, Li, Ru, Lei, Ting-Ying, Wang, Dan, Yang, Xin, Han, Jin, Pan, Min, Zhen, Li, Ou, Yan-Mei, Li, Jian, Li, Fao-Tao, Jing, Xiang-Yi, Li, Dong-Zhi, Liao, Can
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801355/
https://ncbi.nlm.nih.gov/pubmed/29423002
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