Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice

The tumor microenvironment contains unique immune cells, termed myeloid-derived suppressor cells (MDSCs), and tumor-associated macrophages (TAMs) that suppress host anti-tumor immunity and promote tumor angiogenesis and metastasis. Although these cells are considered a key target of cancer immune th...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Hanazawa, Asami, Ito, Ryoji, Katano, Ikumi, Kawai, Kenji, Goto, Motohito, Suemizu, Hiroshi, Kawakami, Yutaka, Ito, Mamoru, Takahashi, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801301/
https://ncbi.nlm.nih.gov/pubmed/29456539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00152
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