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Real Time In-cell NMR: Ribosome Targeted Antibiotics Modulate Quinary Protein Interactions
It is not well understood how ribosome antibiotics affect a wide range of biochemical pathways; changes in RNA-mediated protein quinary interactions and consequent activity inside the crowded cytosol may provide one possible mechanism. We developed real-time (RT) in-cell NMR spectroscopy to monitor...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801172/ https://ncbi.nlm.nih.gov/pubmed/29266932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00938 |
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