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BRAF peptide vaccine facilitates therapy of murine BRAF-mutant melanoma

Approximately, 50% of human melanomas are driven by BRAF mutations, which produce tumors that are highly immunosuppressive and often resistant to vaccine therapy. We introduced lipid-coated calcium phosphate nanoparticles (LCP NPs) as a carrier to efficiently deliver a tumor-specific antigen, the BR...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Liu, Qi, Zhu, Hongda, Liu, Yun, Musetti, Sara, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801101/
https://ncbi.nlm.nih.gov/pubmed/29094184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-2079-7
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