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Dorsal raphé nucleus glucocorticoid receptors inhibit tph2 gene expression in male C57BL/6J mice

The serotonergic dorsal raphé nucleus (DRN) expresses glucocorticoid receptors (GR), and systemic glucocorticoids have been shown to regulate expression and activity of tryptophan hydroxylase isoform 2, the rate-limiting enzyme for serotonin synthesis in brain. We have used intra-DRN injection of ps...

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Bibliografiske detaljer
Udgivet i:Neurosci Lett
Main Authors: Vincent, Melanie Y., Donner, Nina C., Smith, David G., Lowry, Christopher A., Jacobson, Lauren
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800993/
https://ncbi.nlm.nih.gov/pubmed/29174640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2017.11.041
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