SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma

Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread. SCD5 is significantly expressed in primary melanoma, but becomes barely detectable at tumor advanced stages. Look...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Puglisi, Rossella, Bellenghi, Maria, Pontecorvi, Giada, Gulino, Alessandro, Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Mattia, Gianfranco, Carè, Alessandra
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800925/
https://ncbi.nlm.nih.gov/pubmed/29484133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24085
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