SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma

Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread. SCD5 is significantly expressed in primary melanoma, but becomes barely detectable at tumor advanced stages. Look...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Puglisi, Rossella, Bellenghi, Maria, Pontecorvi, Giada, Gulino, Alessandro, Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Mattia, Gianfranco, Carè, Alessandra
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2018
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800925/
https://ncbi.nlm.nih.gov/pubmed/29484133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24085
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