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The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases

Originally identified in yeast, transport protein particle (TRAPP) complexes are Rab GTPase exchange factors that share a core set of subunits. TRAPPs were initially found to act on Ypt1, the yeast orthologue of Rab1, but recent studies have found that yeast TRAPPII can also activate the Rab11 ortho...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Riedel, Falko, Galindo, Antonio, Muschalik, Nadine, Munro, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800803/
https://ncbi.nlm.nih.gov/pubmed/29273580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705068
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