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A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space

Mitochondrial fusion occurs in many eukaryotes, including animals, plants, and fungi. It is essential for cellular homeostasis, and yet the underlying mechanisms remain elusive. Comparative analyses and phylogenetic reconstructions revealed that fungal Fzo1 and animal Mitofusin proteins are highly d...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mattie, Sevan, Riemer, Jan, Wideman, Jeremy G., McBride, Heidi M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800796/
https://ncbi.nlm.nih.gov/pubmed/29212658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611194
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