Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury

Epigenetic predisposition is thought to critically contribute to adult-onset disorders, such as retinal neurodegeneration. The histone methyltransferase, enhancer of zeste homolog 2 (Ezh2), is transiently expressed in the perinatal retina, particularly enriched in retinal ganglion cells (RGCs). We p...

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Vydáno v:PLoS One
Hlavní autoři: Cheng, Lin, Wong, Lucy J., Yan, Naihong, Han, Richard C., Yu, Honghua, Guo, Chenying, Batsuuri, Khulan, Zinzuwadia, Aniket, Guan, Ryan, Cho, Kin-Sang, Chen, Dong Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800601/
https://ncbi.nlm.nih.gov/pubmed/29408885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191853
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