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Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1

The structures of non-human antibodies are largely unstudied despite the potential for the identification of alternative structural motifs and physical properties that will benefit a basic understanding of protein and immune system evolution as well as highlight unexplored motifs to improve therapeu...

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Pubblicato in:PLoS One
Autori principali: Falconer, Daniel J., Barb, Adam W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800599/
https://ncbi.nlm.nih.gov/pubmed/29408873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192123
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