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D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acid secretion and attenuating oxidative stress

Cholestatic liver diseases are important causes of liver cirrhosis and liver transplantation, but few drugs are available for treatment. D-chiro-inositol (DCI), an isomer of inositol found in many Leguminosae plants and in animal viscera, is used clinically for the treatment of polycystic ovary synd...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zhao, Shuang-shuang, Li, Na-ren, Zhao, Wu-li, Liu, Hong, Ge, Mao-xu, Zhang, Yi-xuan, Zhao, Long-yin, You, Xue-fu, He, Hong-wei, Shao, Rong-guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800478/
https://ncbi.nlm.nih.gov/pubmed/28748913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.98
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