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Combing oncolytic adenovirus expressing Beclin-1 with chemotherapy agent doxorubicin synergistically enhances cytotoxicity in human CML cells in vitro

Cancer virotherapy provides a new strategy to treat cancer that can directly kill cancer cells by oncolysis. Insertion of therapeutic genes into the genome of a modified adenovirus, thereby creating a so-called gene-virotherapy that shares the advantages of gene therapy and virotherapy. In this stud...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Pharmacol Sin
Prif Awduron: Li, Li, You, Liang-shun, Mao, Li-ping, Jin, Shen-he, Chen, Xiao-hui, Qian, Wen-bin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800462/
https://ncbi.nlm.nih.gov/pubmed/28905936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.100
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