Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Decysin-1 (ADAMDEC1) is an orphan ADAM-like metalloprotease with unknown biological function and a short domain structure. ADAMDEC1 mRNA has previously been demonstrated primarily in macrophages and mature dendritic cells. Here, we generated monoclonal antibodies (mAbs) against the mature ADAMDEC1 p...

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Publicado en:MAbs
Main Authors: Lund, Jacob, Elimar Bitsch, Anne Mette, Grønbech Rasch, Morten, Enoksson, Mari, Troeberg, Linda, Nagase, Hideaki, Loftager, Mette, Overgaard, Michael Toft, Petersen, Helle Heibroch
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800386/
https://ncbi.nlm.nih.gov/pubmed/29185848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1395541
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