Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis

BACKGROUND: Meningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant. METHODS: We whole-genome sequenced M....

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Ruesen, Carolien, Chaidir, Lidya, van Laarhoven, Arjan, Dian, Sofiati, Ganiem, Ahmad Rizal, Nebenzahl-Guimaraes, Hanna, Huynen, Martijn A., Alisjahbana, Bachti, Dutilh, Bas E., van Crevel, Reinout
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800017/
https://ncbi.nlm.nih.gov/pubmed/29402222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4498-z
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki