Metformin ameliorates experimental-obesity-associated autoimmune arthritis by inducing FGF21 expression and brown adipocyte differentiation

Rheumatoid arthritis (RA) is a systemic autoimmune disease involving excessive inflammation. Recently, RA associated with a metabolic disorder was revealed to be non-responsive to RA medications. Metformin has been reported to have a therapeutic effect on RA and obesity. The aim of this investigatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Mol Med
Egile Nagusiak: Kim, Eun-Kyung, Lee, Seung Hoon, Lee, Seon-Young, Kim, Jae-kyung, Jhun, Joo Yeon, Na, Hyun Sik, Kim, Se-Young, Choi, Jong Young, Yang, Chul Woo, Park, Sung-Hwan, Cho, Mi-La
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2018
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799802/
https://ncbi.nlm.nih.gov/pubmed/29371695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.245
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