Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target

This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy on liver injury and hepatic SIRT1 expressio...

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Publicat a:Exp Mol Med
Autors principals: Tsai, Ming-Shian, Lee, Po-Huang, Sun, Cheuk-Kwan, Chiu, Ting-Chia, Lin, Yu-Chun, Chang, I-Wei, Chen, Po-Han, Kao, Ying-Hsien
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799797/
https://ncbi.nlm.nih.gov/pubmed/29328070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.235
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