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Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target

This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy on liver injury and hepatic SIRT1 expressio...

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Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Tsai, Ming-Shian, Lee, Po-Huang, Sun, Cheuk-Kwan, Chiu, Ting-Chia, Lin, Yu-Chun, Chang, I-Wei, Chen, Po-Han, Kao, Ying-Hsien
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799797/
https://ncbi.nlm.nih.gov/pubmed/29328070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.235
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