Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

The innate immune system processes pathogen-induced signals into cell fate decisions. How information is turned to decision remains unknown. By combining stochastic mathematical modelling and experimentation, we demonstrate that feedback interactions between the IRF3, NF-κB and STAT pathways lead to...

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Vydáno v:Nat Commun
Hlavní autoři: Czerkies, Maciej, Korwek, Zbigniew, Prus, Wiktor, Kochańczyk, Marek, Jaruszewicz-Błońska, Joanna, Tudelska, Karolina, Błoński, Sławomir, Kimmel, Marek, Brasier, Allan R., Lipniacki, Tomasz
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799375/
https://ncbi.nlm.nih.gov/pubmed/29402958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02640-8
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