BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

BMI1, a polycomb group (PcG) protein, plays a critical role in epigenetic regulation of cell differentiation and proliferation, and cancer stem cell self-renewal. BMI1 is upregulated in multiple types of cancer, including prostate cancer. As a key component of polycomb repressive complex 1 (PRC1), B...

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Vydáno v:Nat Commun
Hlavní autoři: Zhu, Sen, Zhao, Dongyu, Yan, Lin, Jiang, Weihua, Kim, Jung-Sun, Gu, Bingnan, Liu, Qipeng, Wang, Rui, Xia, Bo, Zhao, Jonathan C., Song, Gang, Mi, Wenyi, Wang, Rong-Fu, Shi, Xiaobing, Lam, Hung-Ming, Dong, Xuesen, Yu, Jindan, Chen, Kaifu, Cao, Qi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799368/
https://ncbi.nlm.nih.gov/pubmed/29402932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02863-3
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