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Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing

Affinity maturation is the process whereby the immune system generates antibodies of higher affinities during a response to antigen. It is unique in being the only evolutionary mechanism known to operate on a molecule in an organism’s own body. Deciphering the structural mechanisms through which som...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Mishra, Arjun K., Mariuzza, Roy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799246/
https://ncbi.nlm.nih.gov/pubmed/29449843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00117
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