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Pemphigus—A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms
Pemphigus is a severe autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies reducing desmosomal adhesion between epithelial cells. Autoantibodies against the desmosomal cadherins desmogleins (Dsgs) 1 and 3 as well as desmocollin 3 were shown to be pathogenic, wherea...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799217/ https://ncbi.nlm.nih.gov/pubmed/29449846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00136 |
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