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The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction

The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed in detail in patients with this pathology. Here, we report that this FGFR4 variant induces MAPK and STAT3 activation and cau...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Quintanal-Villalonga, Álvaro, Ojeda-Márquez, Laura, Marrugal, Ángela, Yagüe, Patricia, Ponce-Aix, Santiago, Salinas, Ana, Carnero, Amancio, Ferrer, Irene, Molina-Pinelo, Sonia, Paz-Ares, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799167/
https://ncbi.nlm.nih.gov/pubmed/29402970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20570-3
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