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HaSAPPy: A tool for candidate identification in pooled forward genetic screens of haploid mammalian cells
Haploid cells are increasingly used for screening of complex pathways in animal genomes. Hemizygous mutations introduced through viral insertional mutagenesis can be directly selected for phenotypic changes. Here we present HaSAPPy a tool for analysing sequencing datasets of screens using insertiona...
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| Veröffentlicht in: | PLoS Comput Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798846/ https://ncbi.nlm.nih.gov/pubmed/29337991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005950 |
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