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Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors

Induced pluripotent stem cells (iPSCs) or their progeny, derived from human somatic cells, can give rise to functional improvements after intracerebral transplantation in animal models of stroke. Previous studies have indicated that reactive gliosis, which is associated with stroke, inhibits neuroge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Laterza, Cecilia, Uoshima, Naomi, Tornero, Daniel, Wilhelmsson, Ulrika, Stokowska, Anna, Ge, Ruimin, Pekny, Milos, Lindvall, Olle, Kokaia, Zaal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798785/
https://ncbi.nlm.nih.gov/pubmed/29401502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192118
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