Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption

Pulmonary artery endothelial cells (PAECs) express a cation current, I(SOC) (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation. The large molecular weight immunophilin FKBP51 inhibits I(SOC) but not other calcium entry p...

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Bibliografiske detaljer
Udgivet i:Pulm Circ
Main Authors: Hamilton, Caleb L., Kadeba, Pierre I., Vasauskas, Audrey A., Solodushko, Viktoriya, McClinton, Anna K., Alexeyev, Mikhail, Scammell, Jonathan G., Cioffi, Donna L.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798693/
https://ncbi.nlm.nih.gov/pubmed/29261039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045893217749987
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