Topiramate use early in pregnancy and the risk of oral clefts: A pregnancy cohort study

OBJECTIVE: To assess the relative risk of oral clefts associated with maternal use of high and low doses of topiramate during the first trimester for epilepsy and nonepilepsy indications. METHODS: This population-based study nested in the US 2000–2010 Medicaid Analytic eXtract included a cohort of 1...

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Published in:Neurology
Main Authors: Hernandez-Diaz, Sonia, Huybrechts, Krista F., Desai, Rishi J., Cohen, Jacqueline M., Mogun, Helen, Pennell, Page B., Bateman, Brian T., Patorno, Elisabetta
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798655/
https://ncbi.nlm.nih.gov/pubmed/29282333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004857
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