Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study

OBJECTIVE: To examine the risk of postpartum hemorrhage (PPH) and neonatal bleeding complications associated with late-pregnancy exposure to anticonvulsant drugs (ACDs) that induce cytochrome P450 enzymes (ACDi) and alter the metabolism of vitamin K compared to other ACDs. METHODS: We used a populat...

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Pubblicato in:Neurology
Autori principali: Panchaud, Alice, Cohen, Jacqueline M., Patorno, Elisabetta, Huybrechts, Krista F., Desai, Rishi J., Gray, Kathryn J., Mogun, Helen, Hernandez-Diaz, Sonia, Bateman, Brian T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105051/
https://ncbi.nlm.nih.gov/pubmed/29980637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005944
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